You may remember a number of years ago, I talked about reducing interference I was experiencing with my Emotiva XSP-1 pre-amp. The issue had to do with the audio system picking up interference and noise through the pre-amp's "Home Theater Bypass" unbalanced RCA input when connected to my AV receiver. This "HT Bypass" mode is used as a conduit for the front channels and subwoofer out when the AV receiver is in use, typically when I watch movies with multichannel sound.
While this was a bit of a hassle for me, sometimes out of these hurdles and limitations, one is provided with opportunities to explore things like the 8kHz USB PHY packet noise which seeped into my system from the TEAC UD-501 DAC (not an issues these days with my Oppo UDP-205). Playing with things like the Corning Optical USB 3 extender allowed me to lower the noise level. Furthermore, I was also able to show that different USB hubs affected the severity of that 8kHz noise. Remember that much of this investigation was prompted in those days when devices like the AudioQuest USB Jitterbug and the silly single-port-hub known as the UpTone Audio USB Regen were being hyped up by certain websites and forums. To this day, I have not seen any evidence that this stuff improved things like noise level and jitter with reasonable asynchronous USB DACs.